• Coronavirus, Dompé deploys a supercomputer to test effective molecules

Dompé, along with Cineca, the Polytechnic and the University of Milan responded to the call of the EU Tender to find a cure against the disease
 
The Lombard biopharmaceutical company Dompé leads a public-private consortium to find effective treatment against the Coronavirus emergency.

The Consortium takes part in the EU Tender, financed by the Horizon 2020 programme and worth 10 million Euro lining up Cineca of Bologna, the Polytechnic of Milan and the amazing computational skills of their Exscalate platform.

By means of the supercomputers of Cineca, the largest Italian interuniversity computing centre, the Consortium led by Dompé will simulate the behaviour of proteins that allow the virus to replicate. This way, they will be able to virtually test the most effective pharmaceutical molecules to inhibit the virus to then move on to the validation phase in the laboratory. 

The research performed using supercomputers aims at collaborating with traditional research methods, thus shortening the times for the development of drugs. 

Exscalate can examine three million of molecules per second: the Marconi supercomputer on which it relies is a world-class supercomputer. To know more, please read here.
The public-private partnership put in place by Dompé includes 18 European labs from seven different Countries.

This consortium, besides Cineca, the Department of Electronics, Information and Bioengineering of the Polytechnic of Milan, also sees the involvement of other Italian institutions, such as the University of Milan (Department of Pharmaceutical Sciences), the National Institute for Infectious Diseases Lazzaro Spallanzani to which we owe the isolation of the DNA sequence of the Coronavirus in Italy; the University of Naples Federico II, the University of Cagliari, the National Institute of Nuclear Physics (INFN) and Chelonia Applied Science.

This European Tender foresees more assignees. In order to restrict the spreading of the Coronavirus, the European Community has launched a request for expressions of interest for projects aiming at ensuring an effective and coordinated response to this emergency.

The objective of this tender is to define sustainable scientific standards to provide fast responses to any possible pandemic scenario by quickly identifying the most effective drugs. 
In this specific fight against the Coronavirus, the objectives are two: identifying safe drugs (even already existing ones) to treat those already affected by the Covid19 virus and identifying molecules that are able tocurb the pathogenesis of the Coronavirus to put a stop to the infection.
 
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